When Kazahaya Kudo collapsed in the snow one night and on the verge of death, he is rescued by a mysterious young man, Rikuo Himura, who takes him back to a pharmacy named the Green Drugstore.
Kazahaya, apparently running from his past, takes up work at the Green Drugstore alongside Rikuo. He comments that although Rikuo rescued him, he really feels indebted to the store's owner, Kakei, whom he thanks for his current accommodation and job. While their day job is quite simple, the boys are persuaded and, in some cases, practically forced by Kakei to take on strange extra jobs outside the store, which make use of their supernatural powers.
- Kazahaya claims that he and Rikuo are the same age, meaning Rikuo is also 17. Of the two protagonists, Rikuo is much calmer and quieter, and in appearance is taller and more masculine - high-school girls appear to come to the store often specifically to ask Rikuo where some random item is as an excuse to talk to the handsome boy. Rikuo has tattoos on his right shoulder and back, which has been implied to have a connection to Tsukiko.[4] An interesting quirk about Rikuo is that he likes sweet things such as chocolate, which is considered unusual and un-masculine in Japanese society.
- At the very start of the series, Kazahaya is found lying in the snow, having apparently run away from his former home and very nearly freezing to death, before being found by Rikuo, who brings him back to the Green Drugstore. Since then, he has always been trying to earn money so that he might live alone, which is the main reason why he accepts the 'extra' jobs offered by Kakei. He has a supernatural power which is something like psychometry in that he can see the "memories" of things or persons when he touches them; he may also possess some empathic ability as he seems capable of absorbing emotions as well as memories, and on at least one occasion has channeled the present visual perspective of another person (Rikuo).
- While at times he may seem rather helpless, or at least hopelessly naive, he has many skills and abilities which make him highly capable in certain tasks. Specifically, some of his behaviors and abilities seem remarkably similar to a cat, including a heightened sense of smell and vision, several demonstrations of cat-like agility and speed, and his tendency to look like an angry kitten when upset.
- Kazahaya is noted to be 17 at the start of the series, and is smaller, slimmer and has a much more feminine appearance than Rikuo, to the point that he can be accurately described as "pretty". He gets emotional easily, and frequently plays into Rikuo's hands when teased due to his quick temper.
- Kakei is a very beautiful person and has a gentle, kindly air about him. However, he is also very mysterious, and his expression often changes quickly from gentle and kindly to eerie and perhaps even dangerous. He is also noted to have a cruel, and even sadistic side to his nature, although this side of his personality is mostly actualized in almost-subtle teasing.
- It turns out that the reason he opened the Drugstore is in order to protect Kazahaya and everyone he cares about.
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